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Urgent Therapy for Stroke Part I, Pilot Study of Tissue Plasminogen Activator Administered within 90 Minutes Stroke 23:632-640, Brott,T.G.,et al, 1992 See this aricle in Pubmed Article Abstract Seventy-four patients were treated within 90 minute of symptom onset over seven dose tiers of tissue plasminogen activator,ranging from 0.35 mg/kg to 1.08 mg/kg.Intracranial hematoma with associated neurological deterioration occurred in three patients and was related to increasing doses of tissue plasminogen activator(p=0.045).Intracranial hematoma did not occur in any of the 58 patients treated with

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(click to filter results - removes previous filter) adverse drug reaction cerebrovascular accident cerebrovascular accident,acute management of cerebrovascular accident,thrombolytic agents in treatment cerebrovascular accident,time of presentation fibrinolytic agents fibrinolytic agents,complications tissue plasminogen activator,intravenous treatment of neurologic disorder

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